Recombinant human CCL24 1-78 is expressed in E. coli, refolded and purified to yield the mature protein that is secreted from cells after cleavage of the signal peptide as originally described by Forssmann et al. Human CCL23, also designated eotaxin-2 and Macrophage inflammatory protein 3 (MIP-2), attracts eosinophils and resting T cells through activation of the G protein-coupled receptor CCR3. A longer form of CCL24 Additional proteolytic processing at the N terminus (e.g. CCL23 25-99) reportedly yields a more potent form of the chemokine.
Amino Acid Sequence:
|Molecular Weight:||8834.41 Daltons|
|Purity:||Assessed by HPLC, Mass Spectrometry, and NMR.|
|Source:||Human protein expressed in E. coli|
|Physical Form:||Lyophilized powder|
|Solubility:||Freely Soluble in Water|
|Storage Conditions:||Store at -20o C|
Additional comments or descriptive information:
J Exp Med. 1997 Jun 16;185(12):2171-6. https://www.ncbi.nlm.nih.gov/pubmed/?term=9182688
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Recombinant Human CCL24
- Product Code: PFP060
- Availability: In Stock