CCL18 protein is expressed in E. coli, processed, refolded and purified to yield the native, secreted form of the mature chemokine. CCL18, previously identified as DC-CK1 or PARC, is expressed by dendritic cells and is chemotactic for naïve T cells. The 7 transmembrane GPCR CCR8 and the 6 transmembrane protein, membrane-associated phosphatidylinositol transfer protein 3, PITPNM3, are receptors for CCL18. The ligand was shown to have antagonist properties against CCR3.
Amino Acid Sequence:
|Molecular Weight:||7784.11 Daltons|
|Purity:||Assessed by HPLC, Mass Spectrometry, and NMR.|
|Source:||Human protein expressed in E. coli|
|Physical Form:||Lyophilized powder|
|Solubility:||Freely Soluble in Water|
|Storage Conditions:||Store at -20o C|
Additional comments or descriptive information:
Nature. 1997 Jun 12;387(6634):713-7. https://www.ncbi.nlm.nih.gov/pubmed/?term=9192897
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Recombinant Human CCL18 (1-68)
- Product Code: PFP052
- Availability: In Stock