CCL17 protein is expressed in E. coli, processed, refolded and purified to yield the native, secreted form of the mature chemokine.
CCL17 is a ligand for the G protein coupled receptors CCR4 and CCR8, and induces chemotactic migration for T lymphocytes (1), but not monocytes or granulocytes.
Amino Acid Sequence:
ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S
|Molecular Weight:||8079.2 Da|
|Purity:||> 98% by SDS-PAGE, HPLC, MALDI-MS and NMR.|
|Source:||Human protein expressed in E. coli|
|Physical Form:||Lyophilized powder|
|Solubility:||Freely Soluble in Water|
|Storage Conditions:||Store at -20o C|
Additional comments or descriptive information:
(1) Imai T, Baba M, Nishimura M, Kakizaki M, Takagi S, Yoshie O (1997). "The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4". J. Biol. Chem. 272 (23): 15036–42.
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Recombinant Human CCL17
- Product Code: PFP007
- Availability: In Stock