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  • Recombinant Human CXCL14

CXCL14 protein is expressed in E. coli, processed, refolded and purified to yield the native, secreted form of the mature chemokine.

CXCL14 is an orphaned ligand constitutively produced in many normal tissues but is reduced or absent in most cancer cells. CXCL14 is chemotactic for monocytes in the presence of prostaglandin-E2, an attractor and activator of dendritic cells, and chemoattractant for activated NK cells. 

Amino Acid Sequence:

SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE

Molecular Weight:  9415.0 Daltons 
Fusion Tag: N/A
Special Characteristic(s): N/A
Purity: > 98% by SDS-PAGE, HPLC, MALDI-MS and NMR.
Source: Human protein expressed in E. coli
Physical Form: Lyophilized powder
Solubility: Freely Soluble in Water
Storage Conditions: Store at -20o C
   

Additional comments or descriptive information:

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References:

Kurth, I., et al. (2001). "Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development." J Exp Med 194(6): 855-861.

If you publish research with this product, please let us know so we can cite your paper.

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Recombinant Human CXCL14

  • Product Code: CXCL14
  • Availability: In Stock
  • $0.00

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Tags: Cytokine, Chemokine, lymphotactin, CXCL14